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Health Illuminated

A New Era for
Medical Isotopes

A safer, more reliable source of medical isotopes—made in the U.S., helping patients worldwide.

The Challenge

A Fragile System Risks Patient Care

Millions of patients depend on medical isotopes for life-saving scans and cancer treatments. Yet most of the world’s supply still comes from a handful of overseas reactors. Many are more than 60 years old and prone to outages. When these fail, patients wait. Delays can mean the difference between life and death.

We’re building a new path forward. Today, we’re supplying U.S.-made isotopes. At the same time, we’re developing the capability to produce these isotopes using fusion technology. This means a steady supply for providers and researchers now—and an end to chronic shortages in the years ahead.

Improving Patient Outcomes

Theranostics: Uniting Diagnosis and Treatment

Theranostics unites diagnosis and treatment. Providers first use a radioactive isotope to see where disease is. Then, often with the very same isotope, they treat those tumors directly. This dual approach is transforming cancer care, offering more precise detection and more targeted therapies.

Medical screen chartMedical screen chartAn internal view of the human body showing metastatic cancer
A young woman embraces an elderly woman receiving medical treatment
Meeting Global Demand

High Purity, U.S.-Made Lu-177

At the center of this breakthrough is lutetium-177. When paired with a cancer-seeking drug, this medical isotope delivers radiation directly to tumors while sparing nearby tissue. Global demand for Lu-177 is soaring, but supply has been unstable—and most of it is lower in purity.

Our answer is Cassiopeia, one of the largest Lu-177 production facilities in North America. From here we produce Ilumira, our ≥99.9% pure Lu-177 chloride. We’re not only giving patients and physicians a reliable U.S. source, but we’re also building the capacity to meet demand around the world.

Proven Steps Forward for
Medical Isotopes Supply

These milestones trace the progress of our medical isotopes journey:

2015
Argonne National Lab confirms Isotope production process
2016
NRC issues construction permit for Chrysalis.
2019
 Construction begins on Chrysalis
2024
first Ilumira (Lu-177) doses delivered to cancer patients.
2025
Announced agreement to acquire Lantheus’ SPECT
A blue neutron beam
A blue neutron beam
2015
SHINE’S MOLYBDENUM-99 SAMPLE DEMONSTRATES EQUIVALENCE TO REACTOR-BASED PRODUCTION
2016
NUCLEAR REGULATORY COMMISSION ISSUES CONSTRUCTION PERMIT FOR THE CHRYSALIS
2019
WE BELIEVE WE SET A WORLD RECORD FOR A NUCLEAR FUSION REACTION IN A STEADY-STATE SYSTEM, YIELDING 46 TRILLION NEUTRONS PER SECOND
2022
DRUG MASTER FILE FOR N.C.A. LUTETIUM-177 SUBMITTED TO U.S. FOOD AND DRUG ADMINISTRATION
2023
NRC ISSUES FINAL SAFETY EVALUATION REPORT FOR THE CHRYSALIS
Strengthening Supply

Securing Diagnostic Imaging at Scale

Molybdenum-99 (Mo-99) is essential for diagnostic imaging because it decays into technetium-99m (Tc-99m). This is the isotope that typically powers SPECT, the most widely used form of nuclear imaging. Tc-99m enables more than 40 million scans each year, helping providers detect cancer, heart disease, and other serious conditions early.

Yet Mo-99 production remains entirely overseas, with limited capacity to meet demand.

Industrial Scale Production

Building the Future of Mo-99 Supply

We’re solving this challenge with the construction of Chrysalis, the world’s largest medical isotope production facility. Built for scale, it will supply up to 20 million doses of Mo-99 a year and create a reliable U.S. source for a worldwide market.

Chrysalis is engineered with hardened safety systems and redundant production vaults to achieve continuous supply. To reliably move isotopes from plant to patient, we’re also planning vertical integration so providers get a sturdier, U.S.-based supply chain.

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