Isotope Delivery Campus
North Billerica, Massachusetts
SPECT manufacturing and distribution
Where diagnostic imaging gets its supply
We also make the imaging agents used in heart and brain scans and the gas used for lung studies. Manufacturing, quality control, packaging and distribution all run from this one campus, and have since 1969.
Key Facility Stats
PRODUCTS
SPECT diagnostic radiopharmaceuticals
Status
Operational
Distinction
Producing Tc‑99m generators since 1969
Regulatory Status
FDA-registered drug establishment
Distribution
North America and select international markets
“Reliable medicine depends on a reliable supply chain. We’re building it from isotope production through to delivery.”
Mike Rossi, SHINE MEDICAL CEO
THE CAMPUS
Where a week's supply starts
An aerial look at the campus that manufactures and ships SPECT products across North America.
PHOTO GALLERY
Inside SPECT manufacturing and delivery
Four buildings, 218,000 square feet, and the people who keep diagnostic imaging supplied.
WHAT HAPPENS HERE
Capabilities built over five decades
Integrated quality operations
Quality control, calibration, and radiological safety are built into daily operations, so every batch is tested and released before it ships.
SPECT manufacturing at scale
Tc-99m generators, CardioLite and NeuroLite imaging agents used in heart and brain scans, and Xenon Xe-133 gas for lung studies.
An established path to patients
Since 1969, this campus has supplied the generators behind nuclear imaging, from its early adoption to its place in routine care today.
One of two in the country
One of two major U.S. manufacturing sites for these products. Once complete, Chrysalis will make it the only one supplied by domestically produced isotopes.
From production to the patient
The molybdenum-99 (Mo-99) inside Tc-99m generators comes from overseas reactors, most of them nearing the end of their working lives. Because Mo-99 decays quickly, roughly a fifth of any shipment is lost each day it’s in transit. Outages at those reactors have caused recurring shortages, forcing hospitals to reschedule patient tests.
We’re bringing that supply chain home. Our plan is that Chrysalis will produce Mo-99 in Janesville, Wisconsin and ship it to this campus, where it will be loaded into generators and delivered.
Reliable medicine needs a reliable supply chain.
newsroom
SPECT in the news
FACILITIES
One platform, multiple facilities
Across our facilities, the same core capabilities support fusion-system development, neutron testing, medical-isotope production, radiochemistry and commercial operations.
Janesville, Wisconsin
Once complete, we expect Chrysalis to be among the largest medical isotope production facilities of molybdenum-99 (Mo-99) in the world. Producing it in the U.S. with fusion-driven technology, our facility will close a supply gap left by end-of-life reactors overseas and ease real shortages for hospitals.
Janesville, Wisconsin
Cassiopeia produces Ilumira, our non-carrier-added lutetium-177 for cancer treatment. Ilumira’s consistently high quality supports precise, reliable dosing for treatment programs worldwide.
Fitchburg, Wisconsin
Heliopolis is our 47,500 square-foot manufacturing site in Fitchburg, Wis. This is where we design, build and test entire first-of-a-kind fusion systems. Electromagnets, ion sources, tritium handling equipment — if it doesn’t exist yet, we build it here.
Janesville, Wisconsin
Building One runs our radiation effects testing system at approximately 46 trillion fusion reactions per second. Aerospace and defense customers test how their electronics hold up under radiation here, while our radiochemists develop the separation science behind our isotopes and fuel recycling.
Fitchburg, Wisconsin
Our imaging center uses neutron radiography and CT to see inside components and catch flaws invisible to X-rays. We’re one of a limited number of commercial facilities worldwide that can do this without relying on a nuclear reactor.
North Billerica, Massachusetts
Our Isotope Delivery Campus produces and distributes SPECT imaging agents that support millions of diagnostic procedures annually for cardiac, pulmonary, thyroid and other applications for hospitals and imaging centers across North America.