Credibility is built outside your own walls
Anyone can say their technology works. The proof is putting it in front of people who get to decide for themselves.
Government agencies examine projects against criteria we don’t set. Regulators determine whether products are ready to enter new markets. Research institutions and industry partners bring expertise that can challenge an approach and make it stronger.
Government and regulatory review put our work to the test
Making the case for Chrysalis
In April, the U.S. Department of Energy issued a conditional commitment for a loan of up to $263 million to support the completion of Chrysalis, our medical isotope production facility in Janesville, Wisconsin.
Securing that conditional commitment required a detailed DOE review. Before the loan can close and funds can be disbursed, SHINE must meet certain terms outlined by DOE.
We believe that level of scrutiny is valuable. It puts the details of the project in front of outside experts and asks our teams to support the case for what we’re building.
Earning a place in DOE programs
In May, DOE selected us for advanced negotiations under its Surplus Plutonium Utilization Program. We were also selected for two projects under DOE’s Genesis Mission, including work applying AI and advanced computing to nuclear fuel recycling.
Different programs. Different criteria. Different technical problems. The common thread is putting our ideas in front of experts beyond our walls and making the case for our approach.
Meeting the requirements of a new market
In May 2026, we reached a different kind of milestone in nuclear medicine. Ilumira, our lutetium-177 (Lu-177) product, received Centralized Marketing Authorization in Europe, providing us the clearance required to sell the product in the European Union.
Obtaining that authorization requires quality systems, documentation, manufacturing processes and regulatory expertise that meet European standards. For our teams, it was another opportunity to show that the systems surrounding our technology can stand up to expectations established beyond SHINE.
Outside expertise strengthens our approach
Scrutiny from the outside is one way to make the work stronger. Collaborating directly with outside expertise is another.
This year, we began working with Argonne National Laboratory and Case Western Reserve University on high-throughput separation technology for the nuclear fuel recycling process we’re developing. We also joined a GE Vernova-led Advanced Research Projects Agency-Energy (ARPA-E) project focused on nuclear material accountability in fuel recycling.
Nuclear fuel recycling is a multidisciplinary problem. Moving it toward commercial operation requires expertise in chemistry, nuclear engineering, materials, safeguards, process design and other fields. No single organization owns all of that expertise. Solving a problem this complex takes collaboration across disciplines.
Outside experts can challenge an approach, contribute specialized knowledge and surface considerations we may not have encountered on our own. Our teams bring what we’ve learned to the table too, creating opportunities to solve difficult technical problems alongside people who have spent years working on different aspects of these problems.
We believe the result is a stronger approach than any one perspective could produce alone.
What these milestones tell us
A DOE conditional commitment, government program selections, European centralized marketing authorization and new research collaborations are very different milestones. But the processes for each of them have put our technology and ideas in front of people with standards, questions and expertise of their own.
For 16 years, we’ve been building technology intended to work beyond the lab. Doing that means being willing to put what we build to the test.
We believe credibility comes from what you deliver, the standards you meet and the people willing to work alongside you.